Mission
Our mission is to share novel scientific discoveries across all fields of age-related research. We welcome scientists from all disciplines, not only those in traditional gerontology. We aim to spread knowledge of the mechanisms surrounding aging and age-related disease, and ultimately seek to understand how to modulate these pathways to extend healthy life.
Aging | February 6, 2018
The 2nd annual Interventions in Aging Conference, organized by Fusion Conferences and sponsored by the journal Aging, brought hundreds of scientists to Cancun, Mexico to discuss interventional strategies targeting human aging.
Spotlight | February 6, 2018
Alex Zhavoronkov, PhD, a Board Member and Editor of the Journal Aging, wants you to live as long as possible and be younger at every level. “One hundred and fifty is just a number which I recommend everyone use just for subconscious life planning,” said Zhavoronkov. “The longer you plan to live, the longer you will live and the younger you will behave.” Zhavoronkov believes there is a psychological component to aging, and longer lifespan horizons are something we can reasonably achieve, but we first have to believe we can. Zhavoronkov is the Founder, CEO and CSO of Insilico Medicine,… continue reading »

Aging

DNA G-quadruplex role in aging: determining why some people’s brains age better than others

AgingJanuary 18, 2018
Understanding how we age is an important process that is poorly understood, especially aging of the brain. As we age, our brain neurons become older and show changes in how flexible they are and their ability to receive new messages. Aging also affects how well the brain can interpret DNA instructions to repair and sustain brain tissue. These changes mean the brain is less able to mitigate “wear-and-tear” due to aging. Aging happens to everyone, and these changes happen even in healthy brains with no other obvious gene characteristics. However, more serious problems occur when the brain ages poorly, resulting… continue reading »
Aging | January 12, 2018
When you ask someone their age, the answer they give is usually based on their chronological age. But age, alone, is a poor predictor of your lifespan. Researchers set out to study whether biomarkers in your DNA could be used to determine your internal cellular age. These DNA biomarkers occur as part of a vital metabolic process in every cell and every organ of the body (methylation-based biomarkers). These are often referred to as “epigenetic age” or “epigenetic clock” because they can be used to predict a person’s age and estimated lifespan. In a recent article in Aging, Volume 8,… continue reading »
Aging | December 22, 2017
You may recall from your early education that chromosomes are DNA molecules within the nuclei of your cells that contain all or part of the genetic material of an organism. They contain the basic instructions for what make you, you. Everyone has 23 pairs of chromosomes, for a total of 46. At the end of each chromosome is a compound structure called a telomere. As described in Aging, Volume 9, Issue 9, researchers looked at telomere length in the DNA of white blood cells and a natural process in the DNA called that can repress transfer of genetic information (DNA… continue reading »